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Mouse Anti TssM

Technology #2017-290-170512

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Tech Offer 2017-290-170512 Antibodies [PDF]

Anti TssM 170512

Mouse anti- TssM

PRODUCT NAME  Anti – TssM Antibody

BACKGROUND INFORMATION Burkholderia pseudomallei is a Gram-negative saprophyte that is the causative agent of melioidosis, a severe infectious disease endemic in Northern Australia and Southeast Asia. This organism has sparked much scientific interest in the West because of its classification as a potential bioterrorism agent by the U.S. Centers for Disease Control and Prevention. The virulence factor TssM to be responsible for down-regulating host inflammatory response.

PRODUCT DESCRIPTION  This antibody is suitable for studies in inflammatory responses caused by Burkholderia pseudomallei. It is highly specific for TssM protein.

FORMAT  100µg of lyophilized, purified antibody. Reconstitute to 100µl of distilled H2O for 1µg/µl. It contains no additives.

HOST  Mouse CLONALITY  Monoclonal

ISOTYPE  IgG1 

REACTIVITY/SPECIFICITY This antibody is highly specific for TssM protein.

APPLICATIONS  Western Blot (WB)

RECOMMENDED STARTING DILUTIONS WB: 1:200. Optimal dilution has to be determined by the user.

STORAGE  Lyophilized antibody can be kept at 4°C for up to 3 months and should be kept at -20°C  for long-term storage. To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20°C) or for long-term storage (-80°C). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

STABILITY  Minimum 1 year from reception date.

REFERENCES 1. Tan KS, Chen Y, Lim YC, Tan GY, Liu Y, Lim YT, Macary P, Gan YH Suppression of host innate immune response by Burkholderia pseudomallei through the virulence factor TssM. J Immunol. 2010 May 1;184(9):5160-71.

LIMITATIONS This product has to be used for research purposes only.

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