Mouse Chimeric anti-Methoxy Mycolic AcidTechnology #170510
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- Managed By
- Dr Esther Lee (firstname.lastname@example.org@nus.edu.sg) Manager (65)65162837
PRODUCT NAME Anti –
Methoxy Mycolic Acid Antibody
INFOMATION Tuberculosis (TB) is a major cause of mortality and morbidity
due to infectious disease. Mycolic acid, which has been found in patient
sputum samples and comprises a large portion of the mycobacterial cell wall, is
an ideal target. Mab-based detection assays could have a profound effect on
diagnosis of TB. This antibody may be used for detection of mycolic acid in
different species of bacteria strains in TB.
DESCRIPTION This antibody is suitable for TB studies as it is
specific for mycolic acid in bacteria.
FORMAT 100µg of
lyophilized, purified antibody. Reconstitute to 100µl of distilled H2O for
1µg/µl. It contains no additives.
SPECIFICITY This antibody is specific and was able to detect 4.5 ng
of total mycolic acid or methoxy mycolic acid by ELISA.
STARTING DILUTIONS ELISA: 1:1000. Optimal dilution has to be determined by the
antibody can be kept at 4°C for up to 3 months and should be kept at -20°C for
long-term storage. To avoid freeze-thaw cycles, reconstituted antibody should
be aliquoted before freezing for short-term storage (-20°C) or for long-term
storage (-80°C). For maximum recovery of product, centrifuge the original vial
prior to removing the cap. Further dilutions can be made in assay buffer.
STABILITY Minimum 1
year from reception date.
REFERENCES Chan,CE., Zhao BZ.,
Cazenave-Gassiot, A., Pang SW., Bendt,NK., Wenk,MR., MacAry, PA., and
Hanson BJ. Novel phage display-derived mycolic acid-speciﬁc antibodies with
potential for tuberculosis diagnosis. J Lipid Res 2013,54: 2924-2932.
LIMITATIONS This product has to
be used for research purposes only.